 
          Srimuninnimit V, Bianchi G, Szado T, Ratnayake J, Ross G, Valagussa P (2012)
        
        
          Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with
        
        
          locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a
        
        
          randomised multicentre, open-label, phase 2 trial. Lancet Oncol
        
        
          
            13
          
        
        
          (1): 25-32,
        
        
          doi:S1470-2045(11)70336-9 [pii];10.1016/S1470-2045(11)70336-9 [doi]
        
        
          Goldhirsch A, Winer EP, Coates AS, Gelber RD, Piccart-Gebhart M, Thurlimann B,
        
        
          Senn HJ (2013) Personalizing the treatment of women with early breast cancer:
        
        
          highlights of the St Gallen International Expert Consensus on the Primary Therapy of
        
        
          Early Breast Cancer 2013. Ann Oncol
        
        
          
            24
          
        
        
          (9): 2206-2223, doi:mdt303
        
        
          [pii];10.1093/annonc/mdt303 [doi]
        
        
          Goldhirsch A, Wood WC, Coates AS, Gelber RD, Thurlimann B, Senn HJ (2011)
        
        
          Strategies for subtypes--dealing with the diversity of breast cancer: highlights of the
        
        
          St. Gallen International Expert Consensus on the Primary Therapy of Early Breast
        
        
          Cancer 2011. Ann Oncol
        
        
          
            22
          
        
        
          (8): 1736-1747, doi:mdr304 [pii];10.1093/annonc/mdr304
        
        
          [doi]
        
        
          Jones SE, Collea R, Paul D, Sedlacek S, Favret AM, Gore I, Jr., Lindquist DL,
        
        
          Holmes FA, Allison MA, Brooks BD, Portillo RM, Vukelja SJ, Steinberg MS, Stokoe
        
        
          C, Crockett MW, Wang Y, Asmar L, Robert NJ, O'Shaughnessy J (2013) Adjuvant
        
        
          docetaxel and cyclophosphamide plus trastuzumab in patients with HER2-amplified
        
        
          early stage breast cancer: a single-group, open-label, phase 2 study. Lancet Oncol
        
        
          
            14
          
        
        
          (11):
        
        
          1121-1128,
        
        
          doi:S1470-2045(13)70384-X
        
        
          [pii];10.1016/S1470-
        
        
          2045(13)70384-X [doi]
        
        
          Kalsi T, Babic-Illman G, Fields P, Hughes S, Maisey N, Ross P, Wang Y, Harari D
        
        
          (2014) The impact of low-grade toxicity in older people with cancer undergoing
        
        
          chemotherapy. Br J Cancer
        
        
          
            111
          
        
        
          (12): 2224-2228, doi:bjc2014496
        
        
          [pii];10.1038/bjc.2014.496 [doi]
        
        
          Krop IE, Kim SB, Gonzalez-Martin A, LoRusso PM, Ferrero JM, Smitt M, Yu R,
        
        
          Leung AC, Wildiers H (2014) Trastuzumab emtansine versus treatment of physician's
        
        
          choice for pretreated HER2-positive advanced breast cancer (TH3RESA): a
        
        
          randomised, open-label, phase 3 trial. Lancet Oncol
        
        
          
            15
          
        
        
          (7): 689-699, doi:S1470-
        
        
          2045(14)70178-0 [pii];10.1016/S1470-2045(14)70178-0 [doi]
        
        
          Pinder MC, Duan Z, Goodwin JS, Hortobagyi GN, Giordano SH (2007) Congestive
        
        
          heart failure in older women treated with adjuvant anthracycline chemotherapy for
        
        
          breast cancer. J Clin Oncol
        
        
          
            25
          
        
        
          (25): 3808-3815, doi:JCO.2006.10.4976
        
        
          [pii];10.1200/JCO.2006.10.4976 [doi]
        
        
          Rimawi MF, Mayer IA, Forero A, Nanda R, Goetz MP, Rodriguez AA, Pavlick AC,
        
        
          Wang T, Hilsenbeck SG, Gutierrez C, Schiff R, Osborne CK, Chang JC (2013)
        
        
          Multicenter phase II study of neoadjuvant lapatinib and trastuzumab with hormonal
        
        
          therapy and without chemotherapy in patients with human epidermal growth factor
        
        
          receptor 2-overexpressing breast cancer: TBCRC 006. J Clin Oncol
        
        
          
            31
          
        
        
          (14): 1726-
        
        
          1731, doi:JCO.2012.44.8027 [pii];10.1200/JCO.2012.44.8027 [doi]
        
        
          Tolaney SM, Barry WT, Dang CT, Yardley DA, Moy B, Marcom PK, Albain KS, Rugo
        
        
          HS, Ellis M, Shapira I, Wolff AC, Carey LA, Overmoyer BA, Partridge AH, Guo H,